PWE-026 Effects of 26 Weeks of Linaclotide Treatment on Adequate Relief and IBS Severity in Patients with Irritable Bowel Syndrome with Constipation (IBS-C): Abstract PWE-026 Table

IBS-C irritable bowel syndrome with constipation

Tegaserod in the treatment of irritable bowel syndrome (IBS) with constipation as the prime symptom

Irritable bowel syndrome with constipation (IBS-C) as the predominant bowel symptom is a prevalent disorder, characterized by recurring abdominal pain/discomfort, bloating, and constipation, and imposes a significant socio-economic burden. Traditional treatments generally address just one of the multiple IBS symptoms. The efficacy and safety profile of tegaserod, a serotonin 5-HT(4) receptor ag...

Irritable Bowel Syndrome (IBS): Introduction

Irritable Bowel Syndrome (IBS), which is classified as a functional gastrointestinal disorder, is a chronic condition of the lower gastrointestinal tract (Figure 1) that affects as many as 15% of adults in the United States. Not easily characterized by structural abnormalities, infection, or metabolic disturbances, the underlying mechanisms of IBS have for many years remained unclear. Recent re...

Trial on IBS, Irritable Bowel Syndrome

CONDITIONS: Half of the irritable bowel syndrome patients received an exclusion diet that took into account the individual food incompatibilities (detectable by means of a test for food-specific IgG antibodies). The other irritable bowel syndrome patients received a sham diet that did not take into account any incompatibilities. The following symptoms were measured: deterioration and improvemen...

Burden of constipation-predominant irritable bowel syndrome (IBS-C) in France, Italy, and the United Kingdom

BACKGROUND Several studies have examined the effect of irritable bowel syndrome (IBS) on health outcomes in Western Europe, but less research has focused on the constipation subtype (IBS-C). The current study addresses this gap by comparing patients with IBS-C and matched controls for health status, work productivity, and resource utilization. METHODS Data were obtained from the 2010 5EU Nati...